Two Cases of Dedifferentiated Chordoma in the Sacrum

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Two Cases of Dedifferentiated Chordoma in the Sacrum

Dedifferentiated chordoma (DC) is defined as a chordoma containing sarcoma components. DC is distinguished from conventional chordoma by the rapidity of tumor growth and the potential for distant metastasis. We report two cases of DC, which are developed in the sacrum. We reviewed the medical records and imaging studies of 2 patients diagnosed with DC and the literature published. In the first ...

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De novo dedifferentiated chordoma of the sacrum: a case report and review of the literature.

Dedifferentiated chordoma is a rare primary malignant bone cancer. Most cases of dedifferentiated chordoma (DC) are transformed from recurrent chordoma after surgical resection or radiation. The prognosis of DC is extremely poor because of the aggressive nature of the tumor and the potential distant metastases. We report a case of de novo DC of the sacrum in a patient without prior surgical pro...

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Dedifferentiated chordoma: a case report.

Dedifferentiated chordoma, i.e. chordoma with a sarcomatous component, is a rare bone tumor. This case report is of a dedifferentiated chordoma in the sacrococcygeal region in a 50-year-old male. The patient was initially diagnosed as having a leiomyosarcoma at the first medical consultation, but after the tumor recurred it was proven to be a dedifferentiated chordoma. The primary tumor, which ...

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Dedifferentiated Chordoma: A Case Report

Sarcomatous transformation (dedifferentiated chordoma) in chordoma is a very rare condition and has been emphasized as a distinct entity because of its more aggressive clinical course. Here we describe a case of dedifferentiated chordoma arising from the sacrococcygeal region of a 60-year-old man, in third tumor recurrence. This tumor showed features of sarcoma with areas more typical of chordo...

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Familial chordoma. A report of two cases.

We have treated 175 patients with a chordoma over a ten-year period. Only two had a family history of the condition and we describe these in this paper. In one patient the tumour was at the craniocervical junction and in the other the lesion affected the sacrum. We have undertaken a literature review of familial chordoma and have identified chromosomal abnormalities associated with the condition.

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ژورنال

عنوان ژورنال: Korean Journal of Spine

سال: 2015

ISSN: 1738-2262,2093-6729

DOI: 10.14245/kjs.2015.12.3.230